骨骼肌纤维中钙释放与清除的时间进程。
Time course of calcium release and removal in skeletal muscle fibers.
作者信息
Melzer W, Rios E, Schneider M F
出版信息
Biophys J. 1984 Mar;45(3):637-41. doi: 10.1016/S0006-3495(84)84203-4.
Abstract
The transient increase in free myoplasmic calcium concentration due to depolarization of a skeletal muscle fiber is the net result of the release of calcium from the sarcoplasmic reticulum (SR) and its simultaneous removal by binding to various sites and by reuptake into the SR. We present a procedure for empirically characterizing the calcium removal processes in voltage-clamped fibers and for using such characterization to determine the time course of SR calcium release during a depolarizing pulse. Our results reveal a decline of the SR calcium release rate during depolarization that was not anticipated from simple inspection of the calcium transients.
摘要
由于骨骼肌纤维去极化导致的游离肌浆钙浓度的短暂增加，是肌浆网（SR）释放钙以及通过与各种位点结合和再摄取回SR同时进行钙移除的净结果。我们提出了一种经验性地表征电压钳制纤维中钙移除过程的方法，并利用这种表征来确定去极化脉冲期间SR钙释放的时间进程。我们的结果揭示了去极化期间SR钙释放速率的下降，这是简单检查钙瞬变所无法预期的。
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本文引用的文献
1
Calcium transients and intramembrane charge movement in skeletal muscle fibres.骨骼肌纤维中的钙瞬变和膜内电荷移动。
Nature. 1979 May 31;279(5712):391-6. doi: 10.1038/279391a0.
2
Potassium contractures in single muscle fibres.单根肌纤维中的钾挛缩
J Physiol. 1960 Sep;153(2):386-403. doi: 10.1113/jphysiol.1960.sp006541.
3
Stoichiometry of the reactions of calcium with the metallochromic indicator dyes antipyrylazo III and arsenazo III.钙与金属显色指示剂染料安替比拉宗III和偶氮胂III反应的化学计量学
Biophys J. 1981 Dec;36(3):607-21. doi: 10.1016/S0006-3495(81)84755-8.
4
The time-course of Ca2+ exchange with calmodulin, troponin, parvalbumin, and myosin in response to transient increases in Ca2+.响应钙离子瞬时增加，钙离子与钙调蛋白、肌钙蛋白、小清蛋白和肌球蛋白交换的时间进程。
Biophys J. 1981 Jun;34(3):559-69. doi: 10.1016/S0006-3495(81)84868-0.
5
Parvalbumins and muscle relaxation: a computer simulation study.小白蛋白与肌肉松弛：一项计算机模拟研究
J Muscle Res Cell Motil. 1982 Dec;3(4):377-98. doi: 10.1007/BF00712090.
6
Calcium transients evoked by action potentials in frog twitch muscle fibres.青蛙抽动肌纤维动作电位诱发的钙瞬变。
J Physiol. 1982 Dec;333:655-79. doi: 10.1113/jphysiol.1982.sp014474.
7
Sarcoplasmic reticulum calcium release in frog skeletal muscle fibres estimated from Arsenazo III calcium transients.根据偶氮胂III钙瞬变估算青蛙骨骼肌纤维中的肌浆网钙释放。
J Physiol. 1983 Nov;344:625-66. doi: 10.1113/jphysiol.1983.sp014959.
8
Measurement and modification of free calcium transients in frog skeletal muscle fibres by a metallochromic indicator dye.用金属显色指示剂染料测量和改变青蛙骨骼肌纤维中的游离钙瞬变
J Physiol. 1983 Oct;343:161-96. doi: 10.1113/jphysiol.1983.sp014887.
9
Antipyrylazo III, a "middle range" Ca2+ metallochromic indicator.安替比拉宗III，一种“中等范围”的钙离子金属显色指示剂。
Biochemistry. 1978 Apr 18;17(8):1378-86. doi: 10.1021/bi00601a004.
10
Calcium transients in isolated amphibian skeletal muscle fibres: detection with aequorin.离体两栖类骨骼肌纤维中的钙瞬变：用发光蛋白检测
J Physiol. 1978 Apr;277:291-323. doi: 10.1113/jphysiol.1978.sp012273.
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