Bousquet E, Guerrera F, Siracusa M A, Caruso A, Amico-Roxas M
Farmaco Sci. 1984 Feb;39(2):110-9. doi: 10.1002/chin.198435236.
A series of 3-substituted pyridothienopyrimidin-4(3H)-ones has been synthesized from 2,7,9-trimethyl-4H-pyrido[3',2':4,5]thieno-[3,2-d] [ 1,3]oxazin-4-one. These compounds have been evaluated for analgesic, anti-inflammatory and antipyretic activities. The ulcerogenic effect of the compounds has been also studied.
已从2,7,9-三甲基-4H-吡啶并[3',2':4,5]噻吩并[3,2-d][1,3]恶嗪-4-酮合成了一系列3-取代的吡啶并噻吩并嘧啶-4(3H)-酮。已对这些化合物的镇痛、抗炎和解热活性进行了评估。还研究了这些化合物的致溃疡作用。
