Am J Clin Nutr. 1984 Jun;39(6):942-52. doi: 10.1093/ajcn/39.6.942.
Nutrient intake levels and the associations of the nutrients with high-density lipoprotein and low-density lipoprotein cholesterol were studied using cross-sectional data from middle-aged US and USSR men seen at visit 2 of the Lipid Research Clinics Prevalence Study. Differences in nutrient intake in the two countries were small, but statistically significant. The US sample had a higher mean intake of protein, polyunsaturated and monounsaturated fatty acids, and a higher P/S ratio. The USSR sample had higher mean intake of saturated fatty acids, carbohydrate, complex carbohydrate, and sucrose. Correlations between the nutrients and high-density lipoprotein cholesterol were weak and consistently negative for fatty acids, total fat, carbohydrate and its components, and positive for ethanol. The correlations between nutrient intake and low-density lipoprotein cholesterol were even weaker. After adjusting for other factors, nutrient intake had an independent association with high-density lipoprotein cholesterol. Ethanol and carbohydrate showed the strongest association. Nutrient intake also had a modest independent association with low-density lipoprotein cholesterol.
利用脂质研究诊所患病率研究第2次访视时美国和苏联中年男性的横断面数据，研究了营养素摄入水平以及这些营养素与高密度脂蛋白和低密度脂蛋白胆固醇之间的关联。两国在营养素摄入量方面的差异较小，但具有统计学意义。美国样本的蛋白质、多不饱和脂肪酸和单不饱和脂肪酸平均摄入量较高，P/S比值也较高。苏联样本的饱和脂肪酸、碳水化合物、复合碳水化合物和蔗糖平均摄入量较高。脂肪酸、总脂肪、碳水化合物及其成分与高密度脂蛋白胆固醇之间的相关性较弱，且始终呈负相关，而乙醇与高密度脂蛋白胆固醇呈正相关。营养素摄入量与低密度脂蛋白胆固醇之间的相关性更弱。在对其他因素进行调整后，营养素摄入量与高密度脂蛋白胆固醇存在独立关联。乙醇和碳水化合物的关联最为显著。营养素摄入量与低密度脂蛋白胆固醇也存在适度的独立关联。
