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从脂质研究诊所人群中抽取的40至59岁男性的苏联和美国营养摄入量、血浆脂质及脂蛋白情况。

U.S.S.R. and U.S. nutrient intake, plasma lipids, and lipoproteins in men ages 40-59 sampled from Lipid Research Clinics populations.

作者信息

Ingram D D, Thorn M D, Stinnett S S, Deev A D

出版信息

Prev Med. 1985 May;14(3):264-71. doi: 10.1016/0091-7435(85)90055-6.

Abstract

Correlates of high-density lipoprotein (HDL) cholesterol and other lipids and lipoproteins were studied in white men ages 40-59 who were part of the 15% random sample recalled to Visit 2 of the Lipid Research Clinics Program Prevalence Study. Standardized examinations were conducted by two U.S.S.R. and nine U.S. clinics. Mean plasma lipid and lipoprotein cholesterol levels differed significantly between the two countries, with the U.S.S.R. subpopulations having higher mean total plasma and HDL cholesterol levels and HDL/total cholesterol ratios and lower mean triglyceride levels and low-density lipoprotein (LDL)/HDL cholesterol ratios than the U.S. subpopulations. Small, but statistically significant, differences were found in some dietary components. The U.S.S.R. sample had a significantly higher intake of saturated fatty acids, carbohydrates, complex carbohydrates, and kilocalories/kilogram body weight and a significantly lower intake of total fat, polyunsaturated fatty acids, protein, and polyunsaturated/saturated fat ratio. The multiple regression models tested were not major predictors for total plasma cholesterol or LDL cholesterol. Characteristics associated with higher HDL cholesterol levels in both countries were lean body mass, ethanol consumption, abstinence from cigarette smoking, and lower dietary consumption of carbohydrates.

摘要

对年龄在40至59岁的白人男性进行了高密度脂蛋白(HDL)胆固醇以及其他脂质和脂蛋白相关性的研究,这些男性是脂质研究临床项目患病率研究中被召回参加第2次访视的15%随机样本的一部分。由两家苏联诊所和九家美国诊所进行标准化检查。两国之间的平均血浆脂质和脂蛋白胆固醇水平存在显著差异,苏联亚组的平均总血浆和HDL胆固醇水平、HDL/总胆固醇比值较高,而平均甘油三酯水平和低密度脂蛋白(LDL)/HDL胆固醇比值低于美国亚组。在一些饮食成分中发现了虽小但具有统计学意义的差异。苏联样本中饱和脂肪酸、碳水化合物、复合碳水化合物的摄入量以及每千克体重的千卡摄入量显著更高,而总脂肪、多不饱和脂肪酸、蛋白质的摄入量以及多不饱和/饱和脂肪比值显著更低。所测试的多元回归模型并非总血浆胆固醇或LDL胆固醇的主要预测因素。在两国中,与较高HDL胆固醇水平相关的特征包括瘦体重、乙醇消耗、戒烟以及较低的碳水化合物饮食消耗。

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