De Carolis C, De Sanctis G, Perricone R, Moretti C, Fabbri A, Gnessi L, Fraioli F, Fontana L
Experientia. 1984 Jul 15;40(7):738-9. doi: 10.1007/BF01949751.
Beta-endorphin, met-enkephalin, leu-enkephalin and morphine significantly inhibit rosette formation between human T lymphocytes and sheep red blood cells. This effect is completely reversed by naloxone, a specific antagonist, while naloxone by itself does not influence rosette formation. A further link between the immune system and the neuroendocrine system is suggested.