Winter J H, Buckler P W, Bautista A P, Smith F W, Sharp P F, Bennett B, Douglas A S
Thorax. 1983 Aug;38(8):605-8. doi: 10.1136/thx.38.8.605.
The presence or absence of venous thrombosis was determined in 29 patients with an acute exacerbation of chronic obstructive lung disease by the technique of autologous platelet labelling with indium-111. Deep venous thrombosis was diagnosed in 13 patients and in nine of these patients thrombosis was located proximal to the knee--that is, in areas associated with an appreciable risk of pulmonary embolism. One patient died; pulmonary emboli were found at postmortem examination. The incidence of venous thrombosis seen in this study is high enough to suggest that these patients may benefit from prophylactic antithrombotic treatment.
采用铟 - 111自体血小板标记技术,对29例慢性阻塞性肺疾病急性加重期患者进行了静脉血栓形成情况的检测。13例患者被诊断为深静脉血栓形成,其中9例患者的血栓位于膝关节近端,即存在明显肺栓塞风险的部位。1例患者死亡,尸检发现有肺栓塞。本研究中观察到的静脉血栓形成发生率高到足以提示这些患者可能从预防性抗血栓治疗中获益。