Herishanu Y O, Sharpe J A
Ann Neurol. 1983 Jul;14(1):67-72. doi: 10.1002/ana.410140111.
Saccadic intrusions disrupted forward fixation in four patients with bilateral internuclear ophthalmoplegia (INO). Three had multiple sclerosis and one had brainstem infarction. Sporadic bursts of monocular abducting saccades were recorded in either eye. Each saccade was followed by a slower return to midposition. The presence of the INO prevented conjugate saccades of the fellow eye. The adducting phases were faster than convergence eye movements or the glissadic smooth eye movements that sometimes follow saccades. Dynamic overshoot of the abducting saccadic phase may contribute to the relatively rapid adducting phase. The saccadic intrusions of INO are recognized clinically as monocular horizontal oscillation; low-amplitude intrusions are evident only during funduscopy. This distinctive dyskinesia is considered a sign of involvement extrinsic to the medial longitudinal fasciculi in patients with INO.
眼球扫视性干扰破坏了4例双侧核间性眼肌麻痹（INO）患者的向前注视。其中3例患有多发性硬化症，1例患有脑干梗死。在任何一只眼睛中都记录到了单眼外展扫视的散在爆发。每次扫视后都会有较慢的回到中间位置的过程。INO的存在阻止了对侧眼的共轭扫视。内收阶段比集合眼球运动或有时跟随扫视的滑行性平稳眼球运动更快。外展扫视阶段的动态过冲可能导致相对较快的内收阶段。INO的眼球扫视性干扰在临床上被认为是单眼水平振荡；低幅度干扰仅在眼底检查时明显。这种独特的运动障碍被认为是INO患者内侧纵束外受累的一个迹象。
