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[多发性硬化症中临床可检测的眼球运动障碍。对100例患者的研究结果]

[Clinically detectable oculomotor disorders in multiple sclerosis. Results of studies on 100 patients].

作者信息

Müri R M, Meienberg O

出版信息

Nervenarzt. 1987 Mar;58(3):171-4.

PMID:3587451
Abstract

The eye movements of 100 patients with a definite diagnosis of multiple sclerosis were systematically examined using simple clinical tests, whose reliability had been first verified on 40 healthy controls. In 76 of the patients one or more eye movement disorders were observed. The most frequent finding was dissociation of the horizontal saccades due to mainly abortive forms of Internuclear Ophthalmoplegia (INO). In about half of these cases other signs of INO were present. The majority of the remaining pathological findings could be attributed to cerebellar disorders which mainly consisted of saccadic hypermetria, disordered VOR-suppression or rebound nystagmus.

摘要

使用简单的临床测试对100例确诊为多发性硬化症的患者的眼球运动进行了系统检查,这些测试的可靠性首先在40名健康对照者身上得到验证。在76例患者中观察到一种或多种眼球运动障碍。最常见的发现是水平扫视分离,主要是由于核间性眼肌麻痹(INO)的顿挫型。在这些病例中,约一半还存在INO的其他体征。其余大多数病理表现可归因于小脑疾病,主要包括扫视过度、视动性眼震抑制障碍或反弹眼震。

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