Migdal C, Hitchings R
Br J Ophthalmol. 1983 Oct;67(10):655-60. doi: 10.1136/bjo.67.10.655.
A prospective trial of topical antiprostaglandins versus placebo in the treatment of postoperative fistulising surgery followed up for 12 months is described. It is concluded that antiprostaglandins have little place in the management of these cases. A photographic record of evolution of the fistulising bleb is described, together with a scoring system devised for the evolution of the successful fistulising bleb. A comparison is made between appearance and function of the fistulising bleb based on the use of the water drinking test and tonography together with intraocular pressure as tests of bleb function. It is concluded that the appearance of the established bleb alone is an insufficient guide to function, particularly if further surgery--for example, cataract extraction--is required.
本文描述了一项前瞻性试验,该试验对比了局部使用抗前列腺素药物与安慰剂在术后瘘管形成手术治疗中的效果,随访时间为12个月。研究得出结论,抗前列腺素药物在这些病例的治疗中作用不大。文中描述了瘘管形成性水泡演变的照片记录,以及为成功的瘘管形成性水泡演变设计的评分系统。基于饮水试验、眼压描记法以及眼压作为水泡功能测试方法,对瘘管形成性水泡的外观与功能进行了比较。研究得出结论,仅根据已形成的水泡外观不足以判断其功能,特别是在需要进行进一步手术(例如白内障摘除术)的情况下。