Unger W G, Bass M S
Ophthalmologica. 1977;175(3):153-8. doi: 10.1159/000308648.
Irradiation of the pigmented rabbit iris with a moderately low dose of argon laser light (5 applications of 750 mW, 500 micron, 0.5 sec) caused an immediate ocular response consisting of miosis, a rise of intra-ocular pressure and is accompanied by a disruption of the blood-aqueous barrier. Prostaglandin-like material was present in the aqueous humour withdrawn 60 minutes after irradiation. Prior treatment with indomethacin intravenously (20 mg/kg) or benoxinate topically (Novesine; 0.4%) greatly reduced the response and the combined use of the two drugs virtually abolished the ocular changes.
用适度低剂量的氩激光（5次照射，750毫瓦，500微米，0.5秒）照射有色家兔虹膜，会引起即刻的眼部反应，包括瞳孔缩小、眼压升高，并伴有血-房水屏障的破坏。照射60分钟后采集的房水中存在前列腺素样物质。静脉注射吲哚美辛（20毫克/千克）或局部应用丁氧普鲁卡因（诺维辛；0.4%）进行预处理，可大大减轻该反应，两种药物联合使用实际上可消除眼部变化。
