Sheina N I
Farmakol Toksikol. 1983 Jul-Aug;46(4):93-6.
Administration of 2% nicotine to Wistar rats in doses of 1.5 and 5 mg/kg produced functional disorders of the placenta over the entire pregnancy. From the 14th to the 21st day it retarded pregnancy, which at a dose of 1.5 mg/kg was made for by the increased area of the trophoblast elements.
以1.5毫克/千克和5毫克/千克的剂量给Wistar大鼠施用2%的尼古丁，在整个孕期会导致胎盘功能紊乱。从第14天到第21天，它会延缓妊娠，在1.5毫克/千克的剂量下，这是由滋养层细胞面积增加所致。
