顺式不饱和脂肪酸对仓鼠精子顶体反应这一胞吐事件的刺激作用。

Stimulation of an exocytotic event, the hamster sperm acrosome reaction, by cis-unsaturated fatty acids.

作者信息

Meizel S, Turner K O

出版信息

FEBS Lett. 1983 Sep 19;161(2):315-8. doi: 10.1016/0014-5793(83)81032-1.

Abstract

The cis-unsaturated fatty acids oleic, arachidonic and cis-vaccenic stimulated the hamster sperm acrosome reaction in vitro (an exocytotic event which occurs in the sperm head and which is essential for fertilization). The trans-isomers of oleic and vaccenic acids did not stimulate the acrosome reaction, nor did the cis-unsaturated fatty acids petroselenic and docosahexaenoic or the saturated fatty acids lauric, myristic or stearic. This is the first report of a stimulatory effect of cis-unsaturated fatty acids on an exocytic event in an intact viable cell.

摘要

顺式不饱和脂肪酸油酸、花生四烯酸和顺式- 11 -十八碳烯酸在体外刺激仓鼠精子顶体反应（一种发生在精子头部的胞吐事件，对受精至关重要）。油酸和顺式- 11 -十八碳烯酸的反式异构体、顺式不饱和脂肪酸岩芹酸和二十二碳六烯酸以及饱和脂肪酸月桂酸、肉豆蔻酸或硬脂酸均未刺激顶体反应。这是关于顺式不饱和脂肪酸对完整活细胞中的胞吐事件具有刺激作用的首次报道。