Feist D, Wesch H, Schmid-Rüter E
Monatsschr Kinderheilkd (1902). 1978 Jun;126(6):371-4.
Most of the time Wilson's disease becomes clinically evident in childhood by atypical abdominal symptoms. Therefore early diagnosis is very difficult. In four out of eight patients with Wilson's disease, diagnosed relatively early in the Children's Hospital of Heidelberg University, we could demonstrate that each case of liver disease, which cannot be classified, may be suspicious of Wilson's disease. Even normal levels of ceruloplasmin in serum and copper in urine are not inconsistent with Wilson's disease. There is no screening method in infancy. Fatty liver in school children is very suspicious of Wilson's disease.
大多数情况下，威尔逊氏病在儿童期会因非典型腹部症状而在临床上显现出来。因此，早期诊断非常困难。在海德堡大学儿童医院相对较早确诊的8例威尔逊氏病患者中，有4例，我们可以证明，每一例无法分类的肝病病例都可能怀疑是威尔逊氏病。即使血清铜蓝蛋白和尿铜水平正常也不能排除威尔逊氏病。婴儿期没有筛查方法。学龄儿童的脂肪肝很可能是威尔逊氏病。
