Lauwers L F, Daelemans R, Baute L, Verbraeken H
Intensive Care Med. 1983;9(5):283-5. doi: 10.1007/BF01691256.
Pure scopolamine intoxications are extremely rare. We treated a series of severe intoxications exclusively caused by scopolamine and due to the intentional mixing of pure scopolamine into drinks. The clinical course and therapy are reported. On the basis of our experience and a survey of literature, we found physostigmine to be an excellent antidote. The symptomatology of the patients confirms that scopolamine has a dose-related stimulant effect on the central nervous system.
单纯东莨菪碱中毒极为罕见。我们治疗了一系列由东莨菪碱单独引起的严重中毒病例，这些中毒是由于有人故意将纯东莨菪碱混入饮品中所致。本文报告了其临床过程及治疗方法。基于我们的经验和文献调研，我们发现毒扁豆碱是一种极佳的解毒剂。患者的症状表明，东莨菪碱对中枢神经系统具有剂量相关的兴奋作用。
