一种同氮杂甾体酯对雌激素受体的作用。
Effect of an homo-aza-steroidal ester on estrogen receptor.
作者信息
Leclercq G, Devleeschouwer N, Pairas G, Camoutsis C, Catsoulacos P
出版信息
Methods Find Exp Clin Pharmacol. 1983 Jul-Aug;5(6):365-7.
PMID:6621181
Abstract
A new modified steroid esterified with the cytotoxic moiety, p-[N,N-bis(2-chloroethyl)amino]phenyl-acetic acid, has been synthesized and tested for interaction with estrogen receptor and cytotoxic activity on the MCF-7 cell line.
摘要
一种新的经细胞毒性部分对-[N,N-双(2-氯乙基)氨基]苯基乙酸酯化修饰的类固醇已被合成，并测试了其与雌激素受体的相互作用以及对MCF-7细胞系的细胞毒性活性。
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