Pines A, Goldhammer E, Bregman J, Kaplinsky N, Frankl O
Acta Obstet Gynecol Scand. 1983;62(3):279-80. doi: 10.3109/00016348309155809.
Campylobacter enteritis and habitual abortions occurred in a 28-year-old patient suffering from agammaglobulinemia. Campylobacter jejuni has been recently recognized to be a common treatable cause of diarrhea in man. Since bacterial overgrowth of the small intestine is increased in hypo- or agammaglobulinemia, Campylobacter is expected to be found in those patients. As this patient's abortions might have been due to the same infection, Campylobacter should be considered in the differential diagnosis of habitual abortions, especially if associated with diarrheal disease. This treatable disease must be sought in every case of agammaglobulinemia and gastro-intestinal complaints, before complicated diagnostic procedures are performed or potentially toxic drugs are administered.
一名患有无丙种球蛋白血症的28岁患者出现弯曲杆菌肠炎和习惯性流产。空肠弯曲杆菌最近已被确认为人类腹泻的常见可治疗病因。由于在低丙种球蛋白血症或无丙种球蛋白血症患者中,小肠细菌过度生长会增加,因此预计在这些患者中会发现弯曲杆菌。由于该患者的流产可能是由同一感染引起的,因此在习惯性流产的鉴别诊断中应考虑弯曲杆菌,尤其是与腹泻病相关时。在进行复杂的诊断程序或使用潜在有毒药物之前,对于每一例无丙种球蛋白血症和胃肠道不适的病例,都必须寻找这种可治疗的疾病。