Walton B T
Fundam Appl Toxicol. 1983 Jul-Aug;3(4):233-6. doi: 10.1016/s0272-0590(83)80133-x.
Embryos of the cricket Acheta domesticus (L.) have been shown by bioassay to develop gross morphological abnormalities after exposure to a number of complex organic mixtures as well as to display a critical period of teratogen sensitivity and an ability to metabolize xenobiotics during development. Because the assay is simple, inexpensive, short-term (less than two weeks), and objective, it could be useful as an in vivo screen in a hierarchical approach to teratogen detection. Further investigation of cricket embryo responses to known teratogens is needed to establish the predictive value of this assay.
通过生物测定法已表明，家蟋蟀（Acheta domesticus (L.)）的胚胎在接触多种复杂有机混合物后会出现明显的形态异常，并且在发育过程中表现出致畸剂敏感性的关键时期以及代谢外源性物质的能力。由于该测定法简单、廉价、短期（少于两周）且客观，它可用作致畸剂检测分级方法中的体内筛选。需要进一步研究蟋蟀胚胎对已知致畸剂的反应，以确定该测定法的预测价值。
