Koninckx P R, Ide P, Vandenbroucke W, Brosens I A
J Reprod Med. 1980 Jun;24(6):257-60.
After ovulation, peritoneal fluid contains concentrations of progesterone and of 17 beta-estradiol that are 5 to 20 times higher than plasma concentrations in women with ovulatory cycles but not in women with unruptured luteinized follicles. Since viable endometrial cells were found in the peritoneal fluid of over 50% of women, both with and without endometriosis, a new hypothesis is presented about the etiology of pelvic endometriosis and the association of pelvic endometriosis and infertility: pelvic endometriosis could be the consequence of infertility caused by the unruptured luteinized follicle.
排卵后,在有排卵周期的女性中,腹腔液中孕酮和17β-雌二醇的浓度比血浆浓度高5至20倍,但在未破裂的黄素化卵泡的女性中则不然。由于在超过50%的女性腹腔液中发现了活的子宫内膜细胞,无论有无子宫内膜异位症,因此提出了一个关于盆腔子宫内膜异位症的病因以及盆腔子宫内膜异位症与不孕症之间关联的新假说:盆腔子宫内膜异位症可能是未破裂的黄素化卵泡导致不孕的结果。