Hashizume M, Tanaka K, Inokuchi K
Hepatology. 1983 Nov-Dec;3(6):1008-12. doi: 10.1002/hep.1840030619.
Morphologic alterations in the gastric microcirculation in cirrhosis were investigated following infusion of a silicone rubber compound into vessels of the excised stomach which was then cleared with methyl salicylate. In cirrhosis, arteriovenous anastomoses 15 to 50 micron in diameter were present in 5 of 10 patients; spiral arterioles were less than one-tenth as numerous as in stomachs from noncirrhotic patients. The arterioles mainly had a straight pattern and precapillaries, capillaries, and submucosal and subserosal veins were dilated in cirrhotics (p less than 0.05). The number of arteriovenous anastomoses was unrelated to the degree of vascular dilatation and the number of spiral arterioles. These morphological alterations are consistent with decreased arteriovenous flow resistance in the stomach of cirrhotic patients.
通过向切除的胃血管中注入硅橡胶化合物，然后用冬青油清除，研究了肝硬化患者胃微循环的形态学改变。在肝硬化患者中，10例中有5例存在直径为15至50微米的动静脉吻合；螺旋小动脉的数量不到非肝硬化患者胃中的十分之一。肝硬化患者的小动脉主要呈直线型，前毛细血管、毛细血管以及黏膜下和浆膜下静脉均扩张（p<0.05）。动静脉吻合的数量与血管扩张程度和螺旋小动脉的数量无关。这些形态学改变与肝硬化患者胃中动静脉血流阻力降低一致。
