尿中硫代二甘醇酸的灵敏火焰光度检测器分析作为氯乙烯的生物监测指标

Sensitive flame-photometric-detector analysis of thiodiglycolic acid in urine as a biological monitor of vinyl chloride.

作者信息

Chen Z Y, Gu X R, Cui M Z, Zhu X X

出版信息

Int Arch Occup Environ Health. 1983;52(3):281-4. doi: 10.1007/BF00526527.

Abstract

A simple and selective method to detect thiodiglycolic acid (TdGA) in urine by flame-photometric-detector (FPD) of gas chromatograph (GC) is described. The detection limit of this method is less than 1 ng without disturbances. Urine from 64 subjects exposed to different air concentration of vinyl chloride (VCM) from 0.3 ppm to more than 100 ppm in three groups and 78 subjects was detected in this way. A comparison of the results of these groups shows significant differences between the control and two exposed groups.

摘要

描述了一种通过气相色谱仪（GC）的火焰光度检测器（FPD）检测尿液中硫代二甘醇酸（TdGA）的简单且选择性的方法。该方法的检测限低于1纳克且无干扰。用这种方法检测了三组中64名暴露于0.3 ppm至超过100 ppm不同空气氯乙烯（VCM）浓度的受试者以及78名受试者的尿液。这些组结果的比较显示，对照组与两个暴露组之间存在显著差异。