Kelleher J, Mascie-Taylor B H, Davison A M, Bruce G, Losowsky M S
Int J Vitam Nutr Res. 1983;53(3):330-7.
The vitamin status (vitamins A, E, C, Carotene, B1, B2 and B6) of 18 patients receiving maintenance haemodialysis was assessed. All patients were receiving vitamin B1, B2 and B6 supplements and the effect of stopping these supplements on subsequent vitamin status was further studied. Apart from vitamin A, which was significantly increased in all patients, the mean level of all other vitamins was similar to the control group. Despite these normal group means, individual patients could be identified with low or marginally low vitamin C and B2 levels. When the vitamin B complex supplements were stopped, vitamin B2 and B6 remained normal over the subsequent six months maintenance haemodialysis but there was deterioration in vitamin B2 status. Leucocyte vitamin C levels responded well to oral supplements of 400 mg vitamin C per day. This study suggests that vitamin C and B2 supplements are necessary in patients receiving maintenance haemodialysis, other vitamin supplements being unnecessary.
对18例维持性血液透析患者的维生素状态（维生素A、E、C、胡萝卜素、B1、B2和B6）进行了评估。所有患者均接受维生素B1、B2和B6补充剂，并进一步研究了停用这些补充剂对后续维生素状态的影响。除了所有患者的维生素A显著升高外，所有其他维生素的平均水平与对照组相似。尽管这些组均值正常，但仍可识别出个别患者的维生素C和B2水平较低或略低。当停用复合维生素B补充剂时，在随后的六个月维持性血液透析期间，维生素B2和B6仍保持正常，但维生素B2状态有所恶化。白细胞维生素C水平对每日口服400毫克维生素C补充剂反应良好。这项研究表明，接受维持性血液透析的患者需要补充维生素C和B2，其他维生素补充剂则不必要。
