Robinson B, Heid K R, Aldridge T L, Glenn R D
Health Phys. 1983 Oct;45(4):911-21. doi: 10.1097/00004032-198310000-00008.
A Hanford worker received an intake of 241Am by skin absorption and inhalation which was later evaluated to be in excess of 1 mCi. The skin was the main pathway for introduction of 241Am into the body; however inhalation was also a significant pathway. Intensive DTPA therapy prevented 99% of 241Am which entered the blood stream from being deposited in the internal organs. Retention and distribution of 241Am in various internal organs and tissues was determined from sequential measurements in vivo using several arrangements of externally located scintillation detectors. The organ and tissue retention and distribution have been followed for longer than 5 yr. Excretion patterns and estimates of radiation dose to the lung, liver, bone and skin are described.
一名汉福德工厂的工人通过皮肤吸收和吸入摄入了241镅，后来评估其摄入量超过了1毫居里。皮肤是241镅进入人体的主要途径；然而，吸入也是一条重要途径。强化二乙烯三胺五乙酸（DTPA）治疗阻止了进入血流的99%的241镅沉积在内脏器官中。使用外部闪烁探测器的几种布置，通过体内连续测量确定了241镅在各种内脏器官和组织中的滞留和分布情况。对器官和组织的滞留及分布情况进行了长达5年多的跟踪。描述了排泄模式以及对肺、肝、骨和皮肤的辐射剂量估计。
