Hampton J C
Health Phys. 1983 Oct;45(4):933-5. doi: 10.1097/00004032-198310000-00010.
Examination of biopsies from exposed and relatively unexposed areas of the face revealed changes that were consistent with actinic elastic degeneration associated with solar exposure, except in areas in which sources of alpha radiation were detected in the upper dermis. In those areas, particles judged to be ion-exchange resin were found within a few macrophages and extracellularly among connective tissue fibers. Elastic fibers in those areas showed more advanced degenerative change than fibers not closely associated with heavy concentrations of alpha radiation.
对脸部暴露区域和相对未暴露区域的活检样本进行检查发现，除了在上层真皮中检测到α辐射源的区域外，其他变化与日光暴露相关的光化性弹性变性一致。在这些区域，在一些巨噬细胞内以及结缔组织纤维之间的细胞外发现了被判定为离子交换树脂的颗粒。与未紧密关联高浓度α辐射的纤维相比，这些区域的弹性纤维显示出更严重的退行性变化。
