真核生物嗜热性：脂质在嗜热栖热菌生长中的作用。
Eucaryote thermophily: role of lipids in the growth of Talaromyces thermophilus.
作者信息
Wright C, Kafkewitz D, Somberg E W
出版信息
J Bacteriol. 1983 Nov;156(2):493-7. doi: 10.1128/jb.156.2.493-497.1983.
Abstract
The effects of growth temperature on the fatty acid composition of the phospholipids of the fungus Talaromyces thermophilus were investigated. This thermophilic organism was unable to increase the degree of unsaturation of its fatty acids when shifted from high to low growth temperatures. Inhibition of fatty acid synthesis by the antibiotic cerulenin was reversed by the addition of a mixture of palmitic, stearic, and oleic acids and ergosterol. The data obtained were consistent with the hypothesis that the thermophilic character of T. thermophilus is due to metabolic limitations that restrict its ability to regulate membrane fluidity.
摘要
研究了生长温度对嗜热青霉磷脂脂肪酸组成的影响。当这种嗜热生物从高生长温度转变为低生长温度时，其无法提高脂肪酸的不饱和度。添加棕榈酸、硬脂酸、油酸和麦角固醇的混合物可逆转抗生素浅蓝菌素对脂肪酸合成的抑制作用。所获得的数据与以下假设一致：嗜热青霉的嗜热特性是由于代谢限制，从而限制了其调节膜流动性的能力。
相似文献
1
Eucaryote thermophily: role of lipids in the growth of Talaromyces thermophilus.
J Bacteriol. 1983 Nov;156(2):493-7. doi: 10.1128/jb.156.2.493-497.1983.
2
Effect of sterol replacement in vivo on the fatty acid composition of Tetrahymena.
J Biol Chem. 1975 Sep 10;250(17):6998-7005.
3
Incorporation of fatty acids by concanavalin A-stimulated lymphocytes and the effect on fatty acid composition and membrane fluidity.
Biochem J. 1994 Jun 1;300 ( Pt 2)(Pt 2):509-18. doi: 10.1042/bj3000509.
4
Reversal of cerulenin-induced inhibition of phospholipids and sterol synthesis by exogenous fatty acids/sterols in Epidermophyton floccosum.
Biochim Biophys Acta. 1987 Sep 25;921(2):341-6. doi: 10.1016/0005-2760(87)90035-x.
5
[Fatty acid composition of total lipids and phospholipids of membrane preparations of transport ATPases].
Biokhimiia. 1986 Sep;51(9):1499-505.
6
Fatty acids of Trypanosoma cruzi.
Comp Biochem Physiol B. 1982;71(3):397-402. doi: 10.1016/0305-0491(82)90400-x.
7
Effect of temperature on the lipid and fatty acid composition of Yersinia pseudotuberculosis.
New Microbiol. 1995 Jan;18(1):27-33.
8
The biogenesis of mitochondria. 3. The lipid composition of aerobically and anaerobically grown Saccharomyces cerevisiae as related to the membrane systems of the cells.
J Cell Biol. 1968 May;37(2):221-30. doi: 10.1083/jcb.37.2.221.
9
Growth temperature and salinity impact fatty acid composition and degree of unsaturation in peanut-nodulating rhizobia.
Lipids. 2011 May;46(5):435-41. doi: 10.1007/s11745-011-3545-1. Epub 2011 Mar 10.
10
[Fatty acids of actinomycete phospholipids].
Mikrobiologiia. 1980 Sep-Oct;49(5):746-50.
引用本文的文献
1
Lipid Production in Cultivable Filamentous Fungi Isolated from Antarctic Soils: A Comprehensive Study.
Microorganisms. 2025 Feb 25;13(3):504. doi: 10.3390/microorganisms13030504.
2
Thermophilic fungi: their physiology and enzymes.
Microbiol Mol Biol Rev. 2000 Sep;64(3):461-88. doi: 10.1128/MMBR.64.3.461-488.2000.
本文引用的文献
1
Phosphorus assay in column chromatography.
J Biol Chem. 1959 Mar;234(3):466-8.
2
A simple method for the isolation and purification of total lipides from animal tissues.
J Biol Chem. 1957 May;226(1):497-509.
3
The fluidity of cell membranes and its regulation.
Prog Biophys Mol Biol. 1981;38(1):1-104. doi: 10.1016/0079-6107(81)90011-0.
4
Saturated fatty acid-starved cells of Saccharomyces cerevisiae grown in the presence of cerulenin and oleic acid.
J Biochem. 1981 Feb;89(2):523-9. doi: 10.1093/oxfordjournals.jbchem.a133228.
5
Effects of temperature acclimation on Neurospora phospholipids. Fatty acid desaturation appears to be a key element in modifying phospholipid fluid properties.
Biochim Biophys Acta. 1981 Sep 24;665(3):399-407. doi: 10.1016/0005-2760(81)90252-6.
6
The effect of growth temperature on the fatty acid composition of fungi in the order Mucorales.
Can J Microbiol. 1969 Jun;15(6):515-20. doi: 10.1139/m69-089.
7
The lipids of thermophilic fungi: lipid composition comparisons between thermophilic and mesophilic fungi.
Lipids. 1970 Jan;5(1):100-3. doi: 10.1007/BF02531102.
8
Saturated fatty acid mutants in yeast.
Mol Gen Genet. 1971;113(1):1-19. doi: 10.1007/BF00335003.
9
Osmotic properties of spheroplasts from Saccharomyces cerevisiae grown at different temperatures.
J Bacteriol. 1970 May;102(2):311-9. doi: 10.1128/jb.102.2.311-319.1970.
10
Inhibition of fatty acid synthesis by the antibiotic cerulenin. Specific inactivation of beta-ketoacyl-acyl carrier protein synthetase.
Biochim Biophys Acta. 1973 Nov 29;326(2):155-6. doi: 10.1016/0005-2760(73)90241-5.
Zotero 插件