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体重对中年血压正常男性血浆儿茶酚胺模式的影响。

Influence of body weight on plasma catecholamine patterns in middle-aged, normotensive men.

作者信息

Kjeldsen S E, Eide I, Aakesson I, Leren P

出版信息

Scand J Clin Lab Invest. 1983 Jun;43(4):339-42.

PMID:6635540
Abstract

To study the influence of body weight on plasma catecholamine patterns, 34 healthy, normotensive men aged 51 +/- 1 years were stratified into lean (n = 22) and overweight (n = 12) subjects according to Thomas' body mass index. No significant differences on supine arterial and venous catecholamines or standing venous adrenaline and dopamine appeared. However, the lean men had an increased orthostatic venous noradrenaline response (477 +/- 38 ng/l) compared to the overweight (319 +/- 46 ng/l, P less than 0.02). The present findings may indicate an inverse relationship between the sympathetic noradrenergic responsiveness and body weight in healthy, normotensive men while no differences were found in basal catecholamine levels.

摘要

为研究体重对血浆儿茶酚胺模式的影响,根据托马斯体重指数,将34名年龄为51±1岁的健康、血压正常男性分为瘦组(n = 22)和超重组(n = 12)。仰卧位动脉和静脉儿茶酚胺或站立位静脉肾上腺素和多巴胺未见显著差异。然而,与超重组(319±46 ng/l,P<0.02)相比,瘦组男性立位静脉去甲肾上腺素反应增强(477±38 ng/l)。目前的研究结果可能表明,在健康、血压正常的男性中,交感去甲肾上腺素能反应性与体重呈负相关,而基础儿茶酚胺水平未见差异。

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