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用于经皮反射式血氧测定法的搏动血流的分光光度研究。

Spectrophotometric investigation of pulsatile blood flow for transcutaneous reflectance oximetry.

作者信息

Mendelson Y, Cheung P W, Neuman M R, Fleming D G, Cahn S D

出版信息

Adv Exp Med Biol. 1983;159:93-102. doi: 10.1007/978-1-4684-7790-0_9.

DOI:10.1007/978-1-4684-7790-0_9
PMID:6637643
Abstract

A new method to estimate arterial oxygen saturation is suggested based on the presence of the plethysmographic pulse. A prototype skin reflectance oximeter system utilizing a miniature solid state optical transducer has been constructed. Preliminary data collected from a group of volunteers indicated good quantitative correlation between skin reflectance and arterial oxygen saturation as determined by an earlobe oximeter. We are now investigating the dependency of the measurements on various physiological conditions and skin characteristics in order to determine appropriate calibration procedures. This study has demonstrated for the first time that arterial hemoglobin oxygen saturation can be measured quantitatively using transcutaneous reflectance techniques. However, more extensive work is needed to further develop this technique into a viable clinical tool.

摘要

基于体积描记脉搏的存在,提出了一种估计动脉血氧饱和度的新方法。利用微型固态光学传感器构建了一个原型皮肤反射式血氧计系统。从一组志愿者收集的初步数据表明,皮肤反射率与通过耳垂血氧计测定的动脉血氧饱和度之间存在良好的定量相关性。我们现在正在研究测量结果对各种生理条件和皮肤特征的依赖性,以确定合适的校准程序。这项研究首次证明,可以使用经皮反射技术定量测量动脉血红蛋白氧饱和度。然而,需要开展更广泛的工作,以将这项技术进一步发展成为一种可行的临床工具。

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Spectrophotometric investigation of pulsatile blood flow for transcutaneous reflectance oximetry.用于经皮反射式血氧测定法的搏动血流的分光光度研究。
Adv Exp Med Biol. 1983;159:93-102. doi: 10.1007/978-1-4684-7790-0_9.
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Biosensors (Basel). 2023 Jul 5;13(7):711. doi: 10.3390/bios13070711.
2
History of blood gas analysis. VI. Oximetry.血气分析史。VI. 血氧测定法。
J Clin Monit. 1986 Oct;2(4):270-88. doi: 10.1007/BF02851177.
3
Forehead pulse oximetry compared with finger pulse oximetry and arterial blood gas measurement.前额脉搏血氧饱和度测定与手指脉搏血氧饱和度测定及动脉血气测量的比较。
J Clin Monit. 1988 Jul;4(3):223-6. doi: 10.1007/BF01621821.
4
Evaluation of a new reflectance pulse oximeter for clinical applications.
Med Biol Eng Comput. 1991 Sep;29(5):557-61. doi: 10.1007/BF02442331.
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Reflection and transmission pulse oximetry during compromised peripheral perfusion.
J Clin Monit. 1992 Jan;8(1):12-5. doi: 10.1007/BF01618081.
6
Experimental and clinical evaluation of a noninvasive reflectance pulse oximeter sensor.一种无创反射式脉搏血氧饱和度传感器的实验与临床评估
J Clin Monit. 1992 Oct;8(4):257-66. doi: 10.1007/BF01617907.