Chumasov E I, Chalisova N I
Biull Eksp Biol Med. 1983 Nov;96(11):104-7.
Regeneration of the rat peripheral nerve in the lumen of implanted aorta was examined over 4 months. The nerve invaded the vessel with its entire trunk and went out of the distal vessel to the adjacent muscles. Inflammatory infiltrations were observed only outside the implant. Only insignificant number of inflammatory elements were inside the lumen. These conditions favored good regeneration of the nerve without forming a neuroma at the end of the cut nerve. The regenerating myelinized fibers formed spiral-like or bush-like terminals on muscle fibers. The model of directed regeneration of the peripheral nerves in the vascular lumen holds promise for rapid and accurate reinnervation of tissues and organs.
对大鼠周围神经在植入主动脉腔内的再生情况进行了4个月的观察。神经以其整个主干侵入血管，并从远端血管穿出至相邻肌肉。仅在植入物外部观察到炎性浸润。管腔内仅有少量炎性细胞。这些条件有利于神经的良好再生，在切断神经的末端不会形成神经瘤。再生的有髓纤维在肌纤维上形成螺旋状或灌木状终末。血管腔内周围神经定向再生模型有望实现对组织和器官的快速准确再支配。
