Tono-oka T, Matsumoto T, Ueno N, Yashiki N, Matsumoto S
Clin Immunol Immunopathol. 1983 Dec;29(3):333-40. doi: 10.1016/0090-1229(83)90036-3.
Measurements of whole blood chemiluminescence (CL) were carried out by using 0.1 ml of blood to evaluate phagocytic functions from various kinds of pediatric patients. Patients with definite bacterial infections showed an elevated background CL and high peak CL per 1000 granulocytes after stimulation with zymosan. These results suggest that granulocytes of these patients had been preactivated in vivo, their phagocytic and/or metabolic activity being enhanced. Contrary to these results, blood from the patients with viral infections showed almost no abnormalities. Patients with chronic granulomatous disease showed no significant CL by this method similar to conventional ones. This method was also shown to be a useful technique for monitoring the phagocytic functions of blood after granulocyte transfusion.
通过使用0.1毫升血液来测量全血化学发光（CL），以评估各类儿科患者的吞噬功能。确诊为细菌感染的患者在经酵母聚糖刺激后，背景CL升高，每1000个粒细胞的CL峰值较高。这些结果表明，这些患者的粒细胞在体内已被预激活，其吞噬和/或代谢活性增强。与这些结果相反，病毒感染患者的血液几乎没有异常。慢性肉芽肿病患者通过这种方法显示出与传统方法相似的无明显CL。该方法也被证明是监测粒细胞输注后血液吞噬功能的有用技术。
