酗酒及戒酒后的血小板单胺氧化酶和红细胞儿茶酚 - O - 甲基转移酶活性
Platelet monoamine oxidase and erythrocyte catechol-o-methyltransferase activity in alcoholism and controlled abstinence.
作者信息
Agarwal D P, Philippu G, Milech U, Ziemsen B, Schrappe O, Goedde H W
出版信息
Drug Alcohol Depend. 1983 Aug;12(1):85-91. doi: 10.1016/0376-8716(83)90056-x.
PMID:6641500
Abstract
This study substantiates previous reports that low platelet monoamine oxidase (MAO) activity is associated with alcoholism. Catechol-o-methyltransferase (COMT) activity in erythrocytes of alcoholics did not differ from that of controls. In 20 male alcoholics low platelet MAO activity was found during the first 3 days after hospitalization. The MAO activity increased in the next 2 weeks of abstinence and then tended to decrease again.
摘要
本研究证实了先前的报道，即低血小板单胺氧化酶（MAO）活性与酒精中毒有关。酗酒者红细胞中的儿茶酚-O-甲基转移酶（COMT）活性与对照组无差异。在20名男性酗酒者中，住院后的头3天发现血小板MAO活性较低。在戒酒的接下来2周内，MAO活性增加，然后又趋于下降。
相似文献
1
Platelet monoamine oxidase and erythrocyte catechol-o-methyltransferase activity in alcoholism and controlled abstinence.
Drug Alcohol Depend. 1983 Aug;12(1):85-91. doi: 10.1016/0376-8716(83)90056-x.
2
The role of plasma amine oxidase, platelet monoamine oxidase, and red cell catechol-O-methyl transferase in severe behavioral reactions to disulfiram.
Am J Psychiatry. 1979 May;136(5):679-84. doi: 10.1176/ajp.136.5.679.
3
Platelet monoamine oxidase in women with premenstrual syndrome.
Neuropsychobiology. 1977;3(2-3):105-10. doi: 10.1159/000117594.
4
Investigation of a correlation between monoamine oxidase B and catechol-O-methyltransferase activity in human blood cells.
Eur J Pharm Sci. 2000 Dec;12(2):159-63. doi: 10.1016/s0928-0987(00)00151-2.
5
[Determination of monoamine oxidase and catechol-O-methyltransferase in human blood components: methodical aspects (author's transl)].
Arzneimittelforschung. 1976;26(6):1151-2.
6
Low platelet monoamine oxidase activity in human alcoholics.
Med Biol. 1977 Jun;55(3):181-6.
7
Platelet monoamine oxidase in alcoholism.
Biol Psychiatry. 1988 May;24(1):15-24. doi: 10.1016/0006-3223(88)90117-5.
8
Prevalence of low monoamine oxidase function in alcoholism.
Alcohol Clin Exp Res. 1987 Oct;11(5):464-7. doi: 10.1111/j.1530-0277.1987.tb01924.x.
9
10
Familial biochemical and clinical correlates of alcoholics with low platelet monoamine oxidase activity.
Biol Psychiatry. 1979 Apr;14(2):385-94.
Zotero 插件