Sullivan J L, Cavenar J O, Maltbie A A, Lister P, Zung W W
Biol Psychiatry. 1979 Apr;14(2):385-94.
This study substantiates previous reports that low platelet MAO activity is associated with alcoholism. The results also indicate that low platelet MAO activity in alcoholic probands is associated with a higher prevalence of psychiatric hospitalization in first-degree family members as well as alcoholism and suicide attempts among alcoholics. Psychiatrically ill family members of the alcoholic probands with low platelet MAO activity also demonstrate low enzyme activity whereas the well family members have normal enzyme activity.
本研究证实了先前的报告，即血小板单胺氧化酶（MAO）活性低与酗酒有关。结果还表明，酒精中毒先证者的血小板MAO活性低与一级家庭成员中较高的精神病住院患病率以及酗酒者中的酗酒和自杀未遂有关。血小板MAO活性低的酒精中毒先证者的精神病患者家庭成员也表现出低酶活性，而健康家庭成员的酶活性正常。
