Strazzullo P, Trevisan M, Farinaro E, Cappuccio F P, Ferrara L A, de Campora E, Mancini M
Eur Heart J. 1983 Sep;4(9):608-13. doi: 10.1093/oxfordjournals.eurheartj.a061532.
A possible association between dietary salt intake and blood pressure was investigated in an unselected sample of 188 healthy Neapolitan men. In univariate analysis diastolic pressure was positively correlated with age, body mass index and 24-h excretion of sodium, potassium and creatinine, but not with urine volume or sodium: potassium ratio. Systolic pressure was also related to age, body mass index and 24-h sodium, but to a lesser degree. As a high level of intercorrelation was apparent, multivariate analysis was also carried out. Body mass index was shown to be the variable having the largest influence on diastolic pressure variability: nevertheless a significant independent role was still found for 24-h urinary sodium when the latter was included in a regression along with body mass index, age, urine volume and potassium excretion. These results seem to support the possibility that dietary salt has a substantial influence on blood pressure levels.
在188名未经过挑选的健康那不勒斯男性样本中，研究了饮食中盐摄入量与血压之间可能存在的关联。在单变量分析中，舒张压与年龄、体重指数以及24小时钠、钾和肌酐排泄量呈正相关，但与尿量或钠钾比无关。收缩压也与年龄、体重指数和24小时钠有关，但程度较小。由于明显存在高度的相互关联，因此也进行了多变量分析。结果表明，体重指数是对舒张压变异性影响最大的变量：然而，当将24小时尿钠与体重指数、年龄、尿量和钾排泄量一起纳入回归分析时，仍发现其具有显著的独立作用。这些结果似乎支持饮食中的盐对血压水平有重大影响这一可能性。
