Aronson C E
Gen Pharmacol. 1983;14(5):519-23. doi: 10.1016/0306-3623(83)90112-x.
Under an environment of 100% O2, PGBx caused a significant dose dependent decrease in glucose uptake by skeletal muscle from the incubation medium, using the isolated rat diaphragm as a model system. At concentrations of PGBx below 200 micrograms/flask, however, significant alterations in the amount of glucose taken up by the tissues were not observed. The glycogen content of the tissues examined was not changed by the presence of PGBx in the incubation mixture at any of the concentrations studied. When tissues were incubated under room air, however, no PGBx-induced effects on glucose utilization or glycogen concentration were detected.
在100%氧气环境下，以分离的大鼠膈肌为模型系统，PGBx导致骨骼肌从孵育培养基中摄取葡萄糖的量呈显著剂量依赖性下降。然而，当PGBx浓度低于200微克/瓶时，未观察到组织摄取葡萄糖量的显著变化。在所研究的任何浓度下，孵育混合物中PGBx的存在均未改变所检测组织的糖原含量。然而，当组织在室内空气中孵育时，未检测到PGBx对葡萄糖利用或糖原浓度的诱导作用。
