Morris T W, Reece K
Invest Radiol. 1983 Nov-Dec;18(6):526-9. doi: 10.1097/00004424-198311000-00009.
The trapped plasma in the packed red cell portion of the microcapillary hematocrit of hypertonic canine blood was measured with I-125 labelled albumin. Blood osmolalities were raised by the addition of sodium chloride and meglumine/sodium diatrizoate. The trapped plasma was 1.12 +/- 0.15%, 1.75 +/- 0.27% and 1.77 +/- 0.22% at 300, 580, and 723 mOsm/kg, respectively, for sodium chloride solutions. At 924 mOsm/kg some of the blood plus sodium chloride samples hemolyzed. In the group without hemolysis the trapped plasma was 5.84 +/- 1.35% while in the group with hemolysis it measured 12.43 +/- 1.90%. The trapped plasma with diatrizoate solutions was 1.41 +/- 0.11, 2.15 +/- 0.18 and 5.32 +/- 0.56 at 458, 531 and 602 mOsm/kg, respectively. Above an osmolality of 458 mOsm/kg the trapped plasma was significantly greater for the diatrizoate solutions than for the sodium chloride solutions. At osmolalities below 458 mOsm/kg only a small correction is needed for trapped plasma with either sodium chloride or meglumine/sodium diatrizoate solutions.
采用碘-125标记的白蛋白测定高渗犬血微毛细管血细胞比容的红细胞压积部分中截留的血浆。通过添加氯化钠和葡甲胺/泛影酸钠来提高血液渗透压。对于氯化钠溶液，在300、580和723毫渗摩尔/千克时，截留的血浆分别为1.12±0.15%、1.75±0.27%和1.77±0.22%。在924毫渗摩尔/千克时，一些血液加氯化钠样本发生溶血。在未溶血组中，截留的血浆为5.84±1.35%，而在溶血组中为12.43±1.90%。对于泛影酸盐溶液，在458、531和602毫渗摩尔/千克时，截留的血浆分别为1.41±0.11、2.15±0.18和5.32±0.56。在渗透压高于458毫渗摩尔/千克时，泛影酸盐溶液截留的血浆明显高于氯化钠溶液。在渗透压低于458毫渗摩尔/千克时，对于氯化钠或葡甲胺/泛影酸钠溶液截留的血浆仅需进行小的校正。
