Eisenman L M, Sieger D D, Blatt G J
J Comp Neurol. 1983 Nov 20;221(1):53-9. doi: 10.1002/cne.902210105.
The organization of the olivocerebellar projection in the mouse was studied with the use of microinjections of horseradish peroxidase (HRP) or HRP conjugated to wheat germ agglutinin (WGA-HRP). Injections were made in medial, intermediate, and lateral sites along the width of the uvula. The purpose of this investigation was to determine the subnuclear origin of olivary afferents to different mediolateral regions of the uvula. Injections made in or adjacent to the midline of the uvula resulted in the retrograde labeling of cells, bilaterally in the caudal portion of the medial accessory olive (MAO). These labeled cells were located primarily in subnucleus C and nucleus beta of the MAO. Injections into the intermediate part of the uvula resulted in the labeling of cells in the caudal MAO (primarily nucleus beta), the dorsomedial cell column (dmcc), and a few cells in the ventral lamella of the principal olive (vPO). Laterally placed injections produced labeling of cells in dmcc and the vPO. These results are discussed in reference to the parasagittal organization of olivary afferents to the cerebellar cortex in the mouse (Beyerl et al., '82) and the organization of afferents to the involved regions of the inferior olivary (IO) complex. It is suggested that these parasagittal zones in the uvula may play different roles in the control of eye movements.
利用辣根过氧化物酶（HRP）或与麦胚凝集素结合的HRP（WGA-HRP）进行显微注射，研究了小鼠橄榄小脑投射的组织情况。注射部位位于蚓垂宽度方向的内侧、中间和外侧。本研究的目的是确定橄榄传入纤维至蚓垂不同内外侧区域的亚核起源。在蚓垂中线或其附近进行注射，导致内侧副橄榄核（MAO）尾部双侧细胞逆行标记。这些标记细胞主要位于MAO的C亚核和β核。向蚓垂中间部分注射导致尾侧MAO（主要是β核）、背内侧细胞柱（dmcc）和主橄榄核腹侧薄片中的一些细胞被标记。外侧注射使dmcc和vPO中的细胞被标记。结合小鼠小脑皮质橄榄传入纤维的矢状旁组织（Beyerl等人，82年）以及下橄榄核（IO）复合体相关区域的传入纤维组织对这些结果进行了讨论。有人提出，蚓垂中的这些矢状旁区可能在眼球运动控制中发挥不同作用。
