Burrows G W, Alliger C L
J Pharm Sci. 1983 Oct;72(10):1212-3. doi: 10.1002/jps.2600721026.
A high-performance liquid chromatographic method is described which determines cyproheptadine hydrochloride in tablet formulations. Tablets were dissolved in water-acetonitrile (50:50) and analyzed using an octadecylsilane column with a mobile phase of 85% acetonitrile and 15% of an aqueous solution of 0.01 M 1-octanesulfonic acid, 0.5% triethylamine, and 1% acetic acid using UV absorbance detection at 280 nm.
描述了一种高效液相色谱法，用于测定片剂制剂中的盐酸赛庚啶。将片剂溶解于水 - 乙腈（50:50）中，并使用十八烷基硅烷柱进行分析，流动相为85%乙腈与15%的含0.01 M 1 - 辛烷磺酸、0.5%三乙胺和1%乙酸的水溶液，采用280 nm处的紫外吸光度检测。
