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[实验性变应性脑脊髓炎对脑和脊髓磷脂代谢强度的影响]

[Effect of experimental allergic encephalomyelitis on the intensity of phospholipid metabolism in the brain and spinal cord].

作者信息

Zuber V L, Taranova N P

出版信息

Vopr Med Khim. 1978 May-Jun;24(3):322-6.

PMID:664458
Abstract

Metabolism of separate phospholipid fractions was studied in rabbit brain hemispheres, truncus cerebri, cervical and lumbar parts of spinal cord in experimental allergic encephalomyelitis (EAE). Different alterations in metabolic activity of phospholipids in brain and spinal cord were noted in EAE. In brain incorporation of 14C into separate phospholipid fractions was inhibited similarly. In spinal cord the direction of metabolic changes was different: metabolism of phosphatidyl choline and phosphatidyl serine was maximally inhibited in lumbar part and intensity of metabolism of phosphatidyl ethanolamine and phosphatidic acid was increased in cervical part.

摘要

在实验性变应性脑脊髓炎(EAE)中,对兔脑半球、脑干、脊髓颈段和腰段中不同磷脂组分的代谢进行了研究。在EAE中,观察到脑和脊髓中磷脂代谢活性的不同改变。在脑中,14C掺入不同磷脂组分的过程受到类似抑制。在脊髓中,代谢变化的方向不同:腰段中磷脂酰胆碱和磷脂酰丝氨酸的代谢受到最大抑制,而颈段中磷脂酰乙醇胺和磷脂酸的代谢强度增加。

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[Effect of experimental allergic encephalomyelitis on the intensity of phospholipid metabolism in the brain and spinal cord].[实验性变应性脑脊髓炎对脑和脊髓磷脂代谢强度的影响]
Vopr Med Khim. 1978 May-Jun;24(3):322-6.
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