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Albumin binding and hepatic uptake: the importance of model selection.

作者信息

Forker E L, Luxon B A

出版信息

J Pharm Sci. 1983 Oct;72(10):1232-3. doi: 10.1002/jps.2600721038.

DOI:10.1002/jps.2600721038
PMID:6644584
Abstract
摘要

相似文献

1
Albumin binding and hepatic uptake: the importance of model selection.
J Pharm Sci. 1983 Oct;72(10):1232-3. doi: 10.1002/jps.2600721038.
2
Extrapolation of the Hepatic Clearance of Drugs in the Absence of Albumin In Vitro to That in the Presence of Albumin In Vivo: Comparative Assessement of 2 Extrapolation Models Based on the Albumin-Mediated Hepatic Uptake Theory and Limitations and Mechanistic Insights.在缺乏白蛋白的情况下从体外推导出药物的肝脏清除率，到体内存在白蛋白的情况下：基于白蛋白介导的肝摄取理论的 2 种外推模型的比较评估及其局限性和机制见解。
J Pharm Sci. 2018 Jul;107(7):1791-1797. doi: 10.1016/j.xphs.2018.03.012. Epub 2018 Mar 20.
3
The role of albumin in hepatic uptake processes.白蛋白在肝脏摄取过程中的作用。
Prog Liver Dis. 1982;7:71-85.
4
Supplemental Analysis of the Prediction of Hepatic Clearance of Binary Mixtures of Bisphenol A and Naproxen Determined in an Isolated Perfused Rat Liver Model to Promote the Understanding of Potential Albumin-Facilitated Hepatic Uptake Mechanism.补充分析：应用离体灌流大鼠肝脏模型预测双酚 A 和萘普生混合物的肝清除率，以促进对潜在白蛋白促进肝摄取机制的理解。
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Application of the dispersion model to describe disposition kinetics of markers in the dual perfused rat liver.应用弥散模型描述双灌注大鼠肝脏中标记物的处置动力学。
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Theoretical treatment of the distribution and degradation of vascular, interstitial and intracellular albumin.血管、间质和细胞内白蛋白分布与降解的理论处理
J Theor Biol. 1977 Aug 22;67(4):609-23. doi: 10.1016/0022-5193(77)90249-1.
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Effect of a transported ligand on the binding of albumin to rat liver cells.转运配体对白蛋白与大鼠肝细胞结合的影响。
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Hepatocellular uptake of taurocholate in the dog.狗体内牛磺胆酸盐的肝细胞摄取。
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Extracellular distribution of radiolabel obscures specific binding of diethylstilbestrol in mouse skeletal muscle.
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Effects of unstirred Disse fluid, nonequilibrium binding, and surface-mediated dissociation on hepatic removal of albumin-bound organic anions.非搅拌型狄氏液、非平衡结合及表面介导解离对肝脏清除白蛋白结合有机阴离子的影响。
Am J Physiol. 1985 Jun;248(6 Pt 1):G709-17. doi: 10.1152/ajpgi.1985.248.6.G709.

引用本文的文献

1
Can In Vitro-In Vivo Extrapolation Be Successful? Recognizing the Incorrect Clearance Assumptions.体外-体内外推是否可行？认清错误的清除假设。
Clin Pharmacol Ther. 2022 May;111(5):1022-1035. doi: 10.1002/cpt.2482. Epub 2021 Dec 8.
2
Interpretation of Non-Clinical Data for Prediction of Human Pharmacokinetic Parameters: In Vitro-In Vivo Extrapolation and Allometric Scaling.用于预测人体药代动力学参数的非临床数据解读：体外-体内外推法和异速生长标度法
Pharmaceutics. 2019 Apr 5;11(4):168. doi: 10.3390/pharmaceutics11040168.
3
Optimal experimental design for precise estimation of the parameters of the axial dispersion model of hepatic elimination.
用于精确估计肝脏消除轴向扩散模型参数的最优实验设计。
J Pharmacokinet Biopharm. 1998 Oct;26(5):595-615. doi: 10.1023/a:1023229318017.
4
A dispersion model of hepatic elimination: 2. Steady-state considerations--influence of hepatic blood flow, binding within blood, and hepatocellular enzyme activity.肝脏消除的弥散模型：2. 稳态考量——肝血流量、血液内结合以及肝细胞酶活性的影响
J Pharmacokinet Biopharm. 1986 Jun;14(3):261-88. doi: 10.1007/BF01106707.
5
A dispersion model of hepatic elimination: 1. Formulation of the model and bolus considerations.肝脏消除的弥散模型：1. 模型的建立及大剂量注射的考量
J Pharmacokinet Biopharm. 1986 Jun;14(3):227-60. doi: 10.1007/BF01106706.
6
Models of hepatic elimination: comparison of stochastic models to describe residence time distributions and to predict the influence of drug distribution, enzyme heterogeneity, and systemic recycling on hepatic elimination.
J Pharmacokinet Biopharm. 1988 Feb;16(1):41-83. doi: 10.1007/BF01061862.