Nielsen K, Nielsen K K
J Urol. 1983 Dec;130(6):1180-2. doi: 10.1016/s0022-5347(17)51744-9.
There have been 80 cases of carcinoma in exstrophied bladders described previously. We describe another such case in which the specimen was investigated by mucin histochemical and immunohistochemical techniques. The epithelial lining of the bladder was colonic with colon-specific mucin histochemistry and contents of carcinoembryonic antigen. In many foci there were dysplasia of the colonic epithelium and multiple colonic exophytic adenocarcinomas.
此前已有80例膀胱外翻并发癌的病例报道。我们在此描述另一例此类病例,该标本采用了黏液组织化学和免疫组织化学技术进行研究。膀胱的上皮衬里呈结肠型,具有结肠特异性黏液组织化学特征和癌胚抗原含量。在许多病灶中存在结肠上皮发育异常和多发结肠外生性腺癌。