Cunningham E E, Zielezny M A, Venuto R C
JAMA. 1983 Dec 2;250(21):2935-6.
Heroin-associated nephropathy (HAN) is a common cause of end-stage renal disease (ESRD) among 18- to 45-year-old patients in the Buffalo area. To assess the importance of HAN nationwide, a questionnaire was sent to 130 dialysis units or sections of nephrology throughout the United States. Fourteen metropolitan areas represented by 23 respondents reported 98 cases of HAN. Ninety-two patients (93.9%) were black. Black men made up the single largest group, with 77 patients (78.6%). The ESRD had already developed in 66 (67.3%) of the patients with HAN. The occurrence of HAN was high in those units that responded to the questionnaire. These figures, however, do not represent the prevalence of HAN in the United States. The economic impact of treating HAN may be striking. The estimated cost of maintaining just the 66 addicted patients with renal failure on dialysis would be greater than $ 1 million yearly.
海洛因相关性肾病（HAN）是布法罗地区18至45岁患者终末期肾病（ESRD）的常见病因。为评估HAN在全国范围内的重要性，向美国各地130个透析单位或肾病科发送了一份调查问卷。23名受访者代表的14个大都市地区报告了98例HAN病例。92名患者（93.9%）为黑人。黑人男性构成最大的单一群体，有77名患者（78.6%）。66例（67.3%）HAN患者已发展为ESRD。回复调查问卷的单位中HAN的发生率较高。然而，这些数字并不代表美国HAN的患病率。治疗HAN的经济影响可能惊人。仅维持66名患有肾衰竭的成瘾患者进行透析的估计每年费用就将超过100万美元。
