Blumberg A B, Marti H R, Graber C G
JAMA. 1983;250(24):3317-9.
In 20 patients undergoing continuous ambulatory peritoneal dialysis (CAPD), serum ferritin concentration (radioimmunoassay) was compared with bone marrow iron stores (graded semiquantitatively). A close correlation between the two parameters was found. Patients with decreased iron stores (8/20) had serum ferritin concentrations below 70 ng/mL; those with normal or increased iron stores had concentrations above 96 ng/mL. It is concluded that serum ferritin concentrations adequately reflect bone marrow iron stores and are useful as a guide to iron-replacement therapy in patients undergoing CAPD.
对20例持续性非卧床腹膜透析(CAPD)患者,采用放射免疫法测定血清铁蛋白浓度,并与骨髓铁储备(半定量分级)进行比较。发现这两个参数之间存在密切相关性。铁储备减少的患者(8/20)血清铁蛋白浓度低于70 ng/mL;铁储备正常或增加的患者血清铁蛋白浓度高于96 ng/mL。结论是,血清铁蛋白浓度能充分反映骨髓铁储备,可作为指导CAPD患者铁替代治疗的指标。