Frolov V A, Kazanskaia T A, Chibisov S M, Efimova L V
Kardiologiia. 1983 Oct;23(10):98-100.
Left-ventricular contractility and arterial blood levels of free fatty acids were studied experimentally in rabbits with acute focal myocardial ischemia at different hours of the day (12 a. m., 6 p. m., 12 p. m.). All parameters were measured before a myocardial acute-ischemia focus was created, and 15, 20 and 40 minutes after coronary artery ligation. Heart contractility and blood free fatty acid levels were shown to vary throughout the day. In acute focal myocardial ischemia, these parameters also show different patterns of variation. A relationship was demonstrated between the pattern of changes in some contractility indices under acute focal ischemia and blood baseline levels of free fatty acids, which was particularly manifest at 12 p. m., and grew very weak at 12 a. m.
在一天中的不同时间点（上午12点、下午6点、中午12点），对患有急性局灶性心肌缺血的兔子进行了实验研究，观察左心室收缩力和动脉血中游离脂肪酸水平。在创建心肌急性缺血灶之前，以及冠状动脉结扎后15、20和40分钟，对所有参数进行了测量。结果显示，心脏收缩力和血液游离脂肪酸水平在一天中会发生变化。在急性局灶性心肌缺血时，这些参数也呈现出不同的变化模式。研究表明，急性局灶性缺血时某些收缩力指标的变化模式与血液游离脂肪酸的基线水平之间存在关联，这种关联在中午12点时尤为明显，而在上午12点时则变得非常微弱。
