Seńczuk W, Florek E
Med Pr. 1983;34(3):197-203.
Oils IWiOL-3 and OMTI are used to cool the high-power turbines. Their toxicodynamic properties are little known, therefore the studies described herein have been undertaken. The studies did not reveal high acute toxicity, as A-DL50 was found to exceed 15 g/kg of body weight. The simultaneous measurements of cholinesterase activity demonstrated its clear decrease, The studies of subacute toxicity after Lim showed that OMTI after a year's exploitation is the most toxic fluid, as C-LD50 for this compound is 6,21 g/kg of body weight, whereas C-LD50 for the other oils is: 22.449 g/kg of body weight for IW i 02-3-n and 20.93 g/kg of body weight for IWiOL-3-e. Studies of chronic toxicity showed decreased cholinesterase activity and no significant changes in the measurements of certain biochemical and haematological. indices.
IWiOL - 3油和OMTI油用于冷却高功率涡轮机。它们的毒理学特性鲜为人知，因此开展了本文所述的研究。研究未发现高急性毒性，因为经测定急性经口半数致死量（A - DL50）超过15克/千克体重。同时进行的胆碱酯酶活性测量表明其明显下降。对Lim之后的亚急性毒性研究表明，经过一年的使用后，OMTI是毒性最强的液体，该化合物的经皮半数致死量（C - LD50）为6.21克/千克体重，而其他油的经皮半数致死量分别为：IW i 02 - 3 - n为22.449克/千克体重，IWiOL - 3 - e为20.93克/千克体重。慢性毒性研究表明胆碱酯酶活性降低，某些生化和血液学指标的测量未发现显著变化。
