Seńczuk W, Florek E
Med Pr. 1983;34(5-6):375-9.
In experiments on toxicity, IWiOL-3-n aerosol as well as vapours and gases obtained by heating the oil up to 500 degrees C were administered by inhalation to experimental animals. No deaths of animals were recorded however, a significant decrease of cholinesterase activity was noted. The experiments were carried out in the specially constructed experimental chambers and the method of determination IWiOL-3-n in the air was developed. After intratracheal insufflation of IWiOL-3-n, rapid decrease of cholinesterase activity in blood serum was also observed. Tests on dermal toxicity showed very good absorption of the oils through the untouched skin.
在毒性实验中,将IWiOL-3-n气雾剂以及通过将该油加热至500摄氏度所产生的蒸气和气体通过吸入方式给予实验动物。然而,未记录到动物死亡,但观察到胆碱酯酶活性显著下降。实验在专门建造的实验室内进行,并开发了空气中IWiOL-3-n的测定方法。经气管注入IWiOL-3-n后,血清中的胆碱酯酶活性也迅速下降。皮肤毒性试验表明,该油可通过未破损的皮肤被很好地吸收。