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[用于大功率涡轮机冷却的液体的毒理学特性。III. 神经毒性作用]

[Toxicodynamic properties of liquids used for the cooling of high-power turbines. III. Neurotoxic effects].

作者信息

Florek E, Malendowicz L, Seńczuk W

出版信息

Med Pr. 1984;35(1):1-6.

PMID:6738345
Abstract

Results of neurotoxicity studies indicate that preparations IWiOL -3-n, IWiOL -3-e and OMTI administered intragastrically or intraperitoneally induce neurotoxic effects in hens. Those effects are, however, weaker than those of the standard substance, i.e. triorthocresyl . Yet, they get increased in result of IWiOL -3-e, as compared to IWiOL -3-n administration.

摘要

神经毒性研究结果表明,通过胃内或腹腔内给药,制剂IWiOL -3-n、IWiOL -3-e和OMTI会在母鸡身上诱发神经毒性作用。然而,这些作用比标准物质即三邻甲苯基磷酸酯的作用要弱。不过,与给予IWiOL -3-n相比,给予IWiOL -3-e后这些作用会增强。

相似文献

1
[Toxicodynamic properties of liquids used for the cooling of high-power turbines. III. Neurotoxic effects].[用于大功率涡轮机冷却的液体的毒理学特性。III. 神经毒性作用]
Med Pr. 1984;35(1):1-6.
2
[Toxicodynamic properties of liquids used for cooling high-power turbines. I. Acute, subacute and chronic toxicity].用于冷却大功率涡轮机的液体的毒理学特性。I. 急性、亚急性和慢性毒性
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[Toxicodynamic properties of liquids used for cooling high power plants. II. Toxicity determined by inhalation and dermal routes].[用于冷却高功率电厂的液体的毒理学特性。II. 通过吸入和皮肤途径测定的毒性]
Med Pr. 1983;34(5-6):375-9.
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Differential susceptibility of peripheral nerves of the hen to triorthocresyl phosphate and to trauma.母鸡外周神经对磷酸三邻甲苯酯和创伤的易感性差异。
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The significance of background neurologic lesions in acute delayed neurotoxicity studies: a comparison o neurohistopathologic lesions induced in commercial hens by tri-o-tolyl phosphate (TOCP) with those observed in negative control hens.背景神经病变在急性迟发性神经毒性研究中的意义:磷酸三邻甲苯酯(TOCP)诱导商品蛋鸡产生的神经组织病理学病变与阴性对照蛋鸡中观察到的病变的比较。
Neurotoxicology. 1983 Summer;4(2):283-309.
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Tri-ortho-cresyl phosphate (TOCP) decreases the levels of cytoskeletal proteins in hen sciatic nerve.三邻甲苯基磷酸酯(TOCP)降低了母鸡坐骨神经中细胞骨架蛋白的水平。
Toxicol Lett. 2004 Sep 10;152(2):139-47. doi: 10.1016/j.toxlet.2004.04.012.
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Time-dependent changes of lipid peroxidation and antioxidative status in nerve tissues of hens treated with tri-ortho-cresyl phosphate (TOCP).用磷酸三邻甲苯酯(TOCP)处理的母鸡神经组织中脂质过氧化和抗氧化状态的时间依赖性变化。
Toxicology. 2007 Sep 24;239(1-2):45-52. doi: 10.1016/j.tox.2007.06.091. Epub 2007 Jun 27.
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Acute delayed neurotoxicity in hens dosed with tri-ortho-cresyl phosphate (TOCP): correlation between clinical ataxia and neuropathological findings.
Neurotoxicology. 1983 Summer;4(2):271-6.
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Delayed neurotoxic effects caused by triaryl phosphate or triorthocresyl phosphate: a problem of definition.磷酸三芳基酯或磷酸三甲苯酯引起的迟发性神经毒性效应:定义问题
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Decreased phosphofructokinase activity during the development of triorthocresyl-phosphate-induced delayed neuropathy.
Toxicol Lett. 1989 Oct;49(1):35-40. doi: 10.1016/0378-4274(89)90098-2.