Shah K R, West M
Neurosci Lett. 1983 Oct 10;40(3):287-91. doi: 10.1016/0304-3940(83)90053-8.
The effect of concussion on 2-deoxy-D-glucose uptake by various regions of rat brain was investigated. The relative uptake of 2-deoxy-D-glucose was measured at 10 and 20 min post-concussion. The uptake did not change significantly from control rats at 20 min post-concussion. This may be reflective of transient nature of concussion. The uptake was higher in cortex and lower in subcortical structures at 10 min post-concussion. These changes are similar to those reported in spreading cortical depression. Spreading cortical depression may thus be a component of concussion mechanism.
研究了脑震荡对大鼠脑不同区域2-脱氧-D-葡萄糖摄取的影响。在脑震荡后10分钟和20分钟测量2-脱氧-D-葡萄糖的相对摄取量。脑震荡后20分钟时，其摄取量与对照大鼠相比无显著变化。这可能反映了脑震荡的短暂性。脑震荡后10分钟时，皮质摄取量较高，皮质下结构摄取量较低。这些变化与皮层扩散性抑制中所报道的变化相似。因此，皮层扩散性抑制可能是脑震荡机制的一个组成部分。
