Danielczyk W
Wien Klin Wochenschr. 1978 May 26;90(11):377-80.
An abnormal EEG was obtained in altogether 76% of cases in a series of 172 patients with multiple sclerosis. Among the patients with minor neurological defects and a shorter duration of illness, only 26% of the EEGs were abnormal, whereas abnormal recordings were found in a high percentage of bedridden patients with severe neurological disturbances, irrespective of the duration of the illness, i.e. in 83% and 85% of these patients, subdivided according to illness of under or over 10 years' duration, respectively. Hence, severity of multiple sclerosis rather than length of the disease appears to be reflected in an abnormal EEG. Definite prognostic information concerning life expectancy cannot be otained from the EEG. Organic brain syndrom were closely correlated with the severity of EEG changes. Epileptic manifestations were clinically observed in 5.23% of the patients, all of whom manifested pathological EEG recordings.
在一组172例多发性硬化症患者中,共有76%的病例脑电图异常。在神经功能缺损较轻且病程较短的患者中,只有26%的脑电图异常,而在患有严重神经功能障碍的卧床患者中,无论病程长短,脑电图异常记录的比例都很高,即分别根据病程不足或超过10年分组的这些患者中,比例分别为83%和85%。因此,脑电图异常似乎反映的是多发性硬化症的严重程度而非病程长短。无法从脑电图中获得有关预期寿命的确切预后信息。器质性脑综合征与脑电图变化的严重程度密切相关。临床上在5.23%的患者中观察到癫痫表现,所有这些患者的脑电图记录均显示异常。