Larsen K, Skov Jensen B, Axelsen F
Scand J Thorac Cardiovasc Surg. 1983;17(3):311-6. doi: 10.3109/14017438309099370.
A series of 57 esophageal perforations from the period 1963-1982 is reported. They comprised 42 iatrogenic, instrumental perforations and 15 non-iatrogenic, mainly spontaneous and postemetic ruptures. The clinical manifestations were mostly pain, fever, subcutaneous and mediastinal emphysema, pleural effusion and pneumothorax. Esophageal leak was demonstrated in 73% of contrast studies. The overall mortality rate was 25%. It was 21% in cases with primary suture closure and 50% when treatment consisted of drainage. The mortality rate was 19% when treatment was begun within 24 hours and 35% when there was longer delay. Other factors influencing the mortality rate seemed to be type and location of the perforation and age of the patient. Early surgical intervention is advocated for perforation or rupture of the intrathoracic esophagus. Data in the literature and our own findings indicate that also in cervical esophageal perforations early surgical repair is justifiable.
本文报告了1963年至1982年间的57例食管穿孔病例。其中包括42例医源性器械穿孔和15例非医源性穿孔,主要为自发性穿孔和呕吐后破裂。临床表现主要为疼痛、发热、皮下及纵隔气肿、胸腔积液和气胸。73%的造影检查显示有食管漏。总体死亡率为25%。一期缝合关闭病例的死亡率为21%,而采用引流治疗的死亡率为50%。治疗在24小时内开始时死亡率为19%,延迟时间较长时死亡率为35%。其他影响死亡率的因素似乎是穿孔的类型和部位以及患者的年龄。对于胸段食管穿孔或破裂,提倡早期手术干预。文献数据和我们自己的研究结果表明,对于颈段食管穿孔,早期手术修复也是合理的。