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[大肠中含碳水化合物生物聚合物的平衡及其在溃疡性疾病中的损伤机制]

[Balance of carbohydrate-containing biopolymers in the large intestine and mechanism of its impairments in ulcerous disease].

作者信息

Rabinovich P D, Skvortsov V S

出版信息

Vopr Med Khim. 1983 Sep-Oct;29(5):14-7.

PMID:6649527
Abstract

Excretion of carbohydrate-containing components of glycoproteins with feces was studied in patients with ulcerous disease, chronic gastritis, with cancer of stomach and in healthy persons. Content of glycoproteins, especially of fucoglycoproteins, was decreased in intestinal mucous during an acute period of the ulcerous disease. The same phenomenon was observed in epithelium of a distal part of small intestine. Remissions were accompanied by an increase in content of fucoglycoproteins in mucus and epithelium cells. These alterations in balance of glycoproteins were not found in other investigated impairments of the gastro-duodenal system.

摘要

对患有溃疡病、慢性胃炎、胃癌的患者以及健康人粪便中糖蛋白含碳水化合物成分的排泄情况进行了研究。在溃疡病急性期,肠道黏液中糖蛋白尤其是岩藻糖糖蛋白的含量降低。在小肠远端上皮中也观察到了同样的现象。缓解期黏液和上皮细胞中岩藻糖糖蛋白含量增加。在胃十二指肠系统的其他所研究损伤中未发现糖蛋白平衡的这些变化。

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Vopr Med Khim. 1983 Sep-Oct;29(5):14-7.
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