Adye B, Ryan J A
West J Med. 1983 Oct;139(4):471-4.
Cholecystectomy was carried out in 17 teenage girls for cholecystitis at Virginia Mason Hospital, Seattle, between 1971 and 1980. The incidence increased with increasing age. Gallbladder disease was associated with recent pregnancy or birth control pill use (71%), obesity (65%) and family history of gallbladder disease (47%). All but one patient had at least one of these risk factors. No patient had congenital anomalies, blood dyscrasias or other underlying illness. Patients most commonly had recurrent attacks of abdominal pain; seven had symptoms for more than six months. Although the clinical presentations were often mild, six patients had jaundice, three had chemical pancreatitis, one had hemorrhagic pancreatitis, one had pancreatic pseudocyst and abscess and one had a common duct stone. One patient had cholesterosis and 16 had cholelithiasis. All patients were cured by operation. During the same time period, only two boys, both aged 14 years, nonobese and with no family history of gallbladder disease, underwent cholecystectomy, both for acaculous cholecystitis.
1971年至1980年间,西雅图弗吉尼亚梅森医院对17名患有胆囊炎的少女实施了胆囊切除术。发病率随年龄增长而增加。胆囊疾病与近期怀孕或使用避孕药(71%)、肥胖(65%)以及胆囊疾病家族史(47%)有关。除一名患者外,所有患者都至少有这些危险因素中的一项。没有患者有先天性异常、血液系统疾病或其他基础疾病。患者最常见的症状是反复腹痛;7名患者的症状持续超过6个月。尽管临床表现通常较轻,但6名患者出现黄疸,3名患者出现化学性胰腺炎,1名患者出现出血性胰腺炎,1名患者出现胰腺假性囊肿和脓肿,1名患者有胆总管结石。1名患者有胆囊腺肌增生症,16名患者有胆结石。所有患者均通过手术治愈。在同一时期,只有两名14岁的男孩接受了胆囊切除术,他们均非肥胖且无胆囊疾病家族史,两人均因非结石性胆囊炎接受手术。