Rühle K H, Huber G, Klein G, Matthys H
Z Kardiol. 1983 Oct;72(10):604-8.
In 14 patients with chronic obstructive lung disease, the effect of nocturnal oxygen therapy was evaluated. The mean flow of 100% oxygen was 2 l/min. We registered the transcutaneously measured blood gases over 10 h, beginning at 8 p.m. while patients were breathing air, the lowest value of PO2 was mean = 45 mm Hg, and while they were breathing oxygen it was mean = 57 mm Hg. Continuous electrocardiograms showed a reduction of supraventricular arrhythmias, from 180 premature beats over 10 h during inhalation of air to 86 during oxygen inhalation. In each of the 13 patients we found a decrease in frequency of premature ventricular beats (from mean = 141 to mean 54 over 10 h, i.e., from 100% to 25.5% +/- 17.1%. During the 2 h of lowest oxygen saturation, the frequency of ventricular arrhythmias was increased. We expected 20% and registered 38.8%.
对14例慢性阻塞性肺疾病患者进行了夜间氧疗效果评估。100%氧气的平均流速为2升/分钟。我们记录了晚上8点开始的10小时内经皮测量的血气情况，患者呼吸空气时，PO2的最低值平均为45毫米汞柱，呼吸氧气时平均为57毫米汞柱。连续心电图显示室上性心律失常减少，从呼吸空气时10小时内的180次早搏降至吸氧时的86次。在13例患者中，我们发现室性早搏频率均有下降（从10小时内平均141次降至平均54次，即从100%降至25.5%±17.1%）。在氧饱和度最低的2小时内，室性心律失常频率增加。我们预计增加20%，实际记录为增加38.8%。
